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青光眼的严重程度与稳定性:患者认知与客观测量的比较

Severity and stability of glaucoma: patient perception compared with objective measurement.

作者信息

Viswanathan A C, McNaught A I, Poinoosawmy D, Fontana L, Crabb D P, Fitzke F W, Hitchings R A

机构信息

Institute of Ophthalmology, London, England.

出版信息

Arch Ophthalmol. 1999 Apr;117(4):450-4. doi: 10.1001/archopht.117.4.450.

Abstract

OBJECTIVE

To elucidate the relationship between the subjective assessment in patients with glaucoma of (1) the severity of their visual loss, and (2) any deterioration in their visual function and their objective visual fields as measured by computed perimetry.

DESIGN

First, patients completed a questionnaire relating to perceived visual disability and underwent binocular visual field testing. Second, a separate group of patients answered a question about perceived visual deterioration: their monocular visual field tests were analyzed retrospectively by pointwise linear regression to establish stability or deterioration.

SETTING

The Glaucoma Service of a specialist eye hospital, which is a tertiary referral center and serves the local community.

SUBJECTS

One hundred twenty-three patients with glaucoma including 62 for the severity arm of the study and 61 for the progression arm.

MAIN OUTCOME MEASURES

Questionnaire responses, Esterman binocular disability score, and objective visual field deterioration.

RESULTS

Questions strongly associated with Esterman binocular disability scores related to bumping into things, problems with stairs, and finding things that have been dropped. There was a strong association between perceived visual deterioration and measured bilateral visual field deterioration (P<.01).

CONCLUSIONS

There is a strong association between some types of perceived visual disability and the severity of binocular field loss. A patient who notices gradual visual deterioration is twice as likely to have bilateral visual field deterioration as not. The findings in this sample of patients with mild-to-moderate glaucoma challenge the belief that glaucoma is an insidious process in which the symptoms do not appear until the end stage of the disease.

摘要

目的

阐明青光眼患者主观评估(1)其视力丧失严重程度与(2)其视功能的任何恶化情况,以及通过计算机视野计测量的客观视野之间的关系。

设计

首先,患者完成一份与感知视觉残疾相关的问卷,并接受双眼视野测试。其次,另一组患者回答关于感知视力恶化的问题:通过逐点线性回归对他们的单眼视野测试进行回顾性分析,以确定稳定性或恶化情况。

地点

一家专业眼科医院的青光眼诊疗中心,该中心是三级转诊中心,服务当地社区。

研究对象

123例青光眼患者,其中62例纳入研究的严重程度组,61例纳入进展组。

主要观察指标

问卷回答、埃斯特曼双眼残疾评分和客观视野恶化情况。

结果

与埃斯特曼双眼残疾评分密切相关的问题涉及撞到东西、上下楼梯困难以及找到掉落物品。感知视力恶化与测量的双侧视野恶化之间存在密切关联(P<0.01)。

结论

某些类型的感知视觉残疾与双眼视野丧失的严重程度之间存在密切关联。注意到视力逐渐恶化的患者出现双侧视野恶化的可能性是未注意到者的两倍。该轻度至中度青光眼患者样本的研究结果挑战了青光眼是一种隐匿性疾病,直到疾病末期才会出现症状的观点。

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