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[关联性负变与精神障碍]

[Contingent negative variation and mental disorders].

作者信息

Timsit-Berthier M

出版信息

Acta Psychiatr Belg. 1976 Jul-Aug;76(4):521-50.

PMID:1020686
Abstract

This work, dealing with negative contingency variation (NCV) in mental patients, is in the general frame of research aiming at establishing correlations between biological phenomenons and psychic entities. The results can be examined in three different directions. 1. In the electrophysiological perspective they have individualized a series of physiological forms and brought a real nomenclature. 2. In an electro-clinical perspective, they have allowed to oppose normal curves (NCV, type I, responses to sensory stimulations type A, B, C and motor potential type N) and abnormal curves (NCV zero or type III, IV, responses type D and motor potential type P). One must however stress that this distinction is only valid if one studies adult subjects and awaken, and contributes only an index of non specific morbidity. Furthermore, considering two more electrophysiological criteria--the mode of combination of various curves and the stability of NCV--can help establishing a severity scale and modeling the above data. 3. In a physiopathological perspective, they have lead to discussing two hypotheses concerning the functional signification of prolonged NCV; one being a prolonged state of awaiting, the other a mode of particular reaction to imperative stimulation, and to demonstrate that it is not possible to consider only one and same system to explain all clinical categories. Thus, in this new area of slow cerebral potentials, as in clinical electroencephalography, is illustrated the teaching of the functional electroencephalography through the school of Paris where similar electric patterns have different significations when present in opposed psychological organisations.

摘要

这项针对精神病患者负性偶联变异(NCV)的研究,处于旨在建立生物现象与心理实体之间关联的总体研究框架内。研究结果可从三个不同方向进行审视。1. 从电生理学角度来看,他们已确定了一系列生理形式并给出了一个切实可行的命名法。2. 从电临床角度而言,他们得以区分正常曲线(NCV,I型,对A、B、C型感觉刺激的反应以及N型运动电位)和异常曲线(NCV为零或III、IV型,D型反应以及P型运动电位)。然而必须强调的是,只有在研究成年觉醒受试者时,这种区分才有效,且仅提供了非特异性发病率的一个指标。此外,考虑另外两个电生理标准——各种曲线的组合方式以及NCV的稳定性——有助于建立一个严重程度量表并对上述数据进行建模。3. 从生理病理学角度来看,他们引发了关于NCV延长的功能意义的两种假设的讨论;一种是延长的等待状态,另一种是对紧急刺激的特殊反应模式,并证明不可能仅用一个相同的系统来解释所有临床类别。因此,在这个慢脑电位的新领域,如同在临床脑电图中一样,通过巴黎学派的功能性脑电图学说得以体现,即在相反的心理组织中出现类似的电模式时具有不同的意义。

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