Van Renynghe de Voxvrie G, De Bie M
Acta Psychiatr Belg. 1976 Jul-Aug;76(4):688-95.
Dipiperon drops 30-180 mg/day were given for eight weeks to 29 children with character neuroses and behavioural disorders. A 16-item rating-scale covering several features of behaviour disorder was completed by a psychologist and a teacher independent from each other. The individual number of pathological scores showed a decrease already within the first treatment week and a further decrease by the end of the trial, especially for the items of capriciousness, obstinacy, irritability and restlessness. The therapeutic benefit was not accompanied by an adverse effect on the school performance of the children. No side-effects were reported or observed.
对29名患有性格神经症和行为障碍的儿童,给予每日30 - 180毫克的双哌丙醇滴剂,持续治疗八周。一名心理学家和一名教师彼此独立,完成了一份涵盖行为障碍若干特征的16项评定量表。病理评分的个体数量在治疗的第一周内就已显示出下降,到试验结束时进一步下降,尤其是任性、固执、易怒和烦躁不安等项目。治疗效果并未对儿童的学业成绩产生不利影响。未报告或观察到任何副作用。