Haegeman J, Duyck F
Acta Psychiatr Belg. 1978 Mar-Apr;78(2):392-8.
Nineteen severely mentally handicapped female patients (15-24 years), whose IQ was between less than 30 to 36, were treated with pipamperone (Dipiperon) because of behavioral disturbances. The dose varied from 40 to 180 mg/day spread over one to three intakes. The duration of treatment ranged between two and ten months. The therapeutic effect was evaluated by means of a 12-item rating-scale. A statistically significant improvement was obtained for nine of the 12 items. Overall improvement was very good in two, good in ten, moderate in five, and insufficient in two patients. Serious side-effects were not observed.
19名重度智力障碍女性患者（年龄15 - 24岁），智商在30以下至36之间，因行为障碍接受了匹泮哌隆（双哌隆）治疗。剂量为每日40至180毫克，分1至3次服用。治疗持续时间为2至10个月。通过一个12项评定量表评估治疗效果。12项中有9项获得了统计学上的显著改善。总体改善情况为：2例非常好，10例良好，5例中等，2例不足。未观察到严重副作用。
