Rutty G N, Smith C M, Malia R G
Department of Forensic Pathology, Medico-Legal Centre, Sheffield, UK.
Am J Forensic Med Pathol. 1999 Mar;20(1):48-51. doi: 10.1097/00000433-199903000-00012.
Hemorrhagic disease of the newborn (HDN) is usually a self-limiting hemorrhagic disorder of childhood that occurs as a result of vitamin K deficiency. It may be defined as early or late form depending on the time of onset related to birth. HDN is recognized as one of several bleeding disorders that can mimic the findings of nonaccidental head injury and may lead to a mistaken diagnosis of child abuse. We present a single fatal case of late-onset HDN with illustration of hematologic assays that can be performed to assist the pathologist in making the correct diagnosis of HDN.
新生儿出血性疾病（HDN）通常是一种儿童期自限性出血性疾病，由维生素K缺乏引起。根据发病时间与出生的关系，可分为早发型或晚发型。HDN被认为是几种可能模拟非意外性头部损伤表现的出血性疾病之一，可能导致虐待儿童的误诊。我们报告一例晚发型HDN致死病例，并举例说明可进行的血液学检测，以协助病理学家正确诊断HDN。
