与溃疡性结肠炎相关的线状IgA大疱性皮肤病

Linear IgA bullous dermatosis associated with ulcerative colitis.

作者信息

Chi H I, Arai M

机构信息

Department of Dermatology, Odaira Memorial Tokyo Hitachi Hospital, Japan.

出版信息

J Dermatol. 1999 Mar;26(3):150-3. doi: 10.1111/j.1346-8138.1999.tb03445.x.

DOI:10.1111/j.1346-8138.1999.tb03445.x

PMID:10209920

Abstract

A 41-year-old woman developed skin vesicles one week before examination. She had been suffering from ulcerative colitis since the age of 30. Histologic examination of a vesicle showed a subepidermal bulla accompanied by mononuclear leukocyte infiltration intermingled with eosinophils and neutrophils. Eosinophilia was also noted. Direct immunofluorescent test revealed linear deposits of IgA in the basement membrane zone.

摘要

一名41岁女性在检查前一周出现皮肤水疱。她自30岁起就患有溃疡性结肠炎。对一个水疱进行组织学检查显示表皮下水疱，伴有单核白细胞浸润，并混有嗜酸性粒细胞和中性粒细胞。还发现有嗜酸性粒细胞增多。直接免疫荧光试验显示在基底膜区有IgA线状沉积。