Hayakawa K, Shiohara T, Yagita A, Nagashima M
Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan.
J Am Acad Dermatol. 1992 Jan;26(1):110-3. doi: 10.1016/0190-9622(92)70017-a.
A case of linear IgA bullous dermatosis associated with rheumatoid arthritis is described. The eruption consisted of multiple irregular erythematous plaques and small numbers of tense vesicles mainly on the trunk. An immunofluorescence study showed linear IgA and IgG deposition along the basement membrane zone, whereas C3 deposition was not found. IgA or IgG anti-basement membrane zone antibody was not detected in the serum. Treatment with dapsone resulted in good control of the eruption. Coexistence of linear IgA bullous dermatosis and rheumatoid arthritis has not been reported previously.
本文描述了一例与类风湿关节炎相关的线状IgA大疱性皮肤病病例。皮疹主要由躯干上的多个不规则红斑斑块和少量紧张性水疱组成。免疫荧光研究显示沿基底膜带有线状IgA和IgG沉积,而未发现C3沉积。血清中未检测到IgA或IgG抗基底膜带抗体。氨苯砜治疗使皮疹得到了良好控制。线状IgA大疱性皮肤病与类风湿关节炎并存此前未见报道。