Shield P W, Nolan G R, Phillips G E, Cummings M C
Queensland Cytology Service, Queensland Health Pathology Service, Royal Brisbane Hospital.
Med J Aust. 1999 Mar 15;170(6):255-8. doi: 10.5694/j.1326-5377.1999.tb127744.x.
To evaluate the use of the ThinPrep method to reduce rates of unsatisfactory Papanicolaou (Pap) smears in women in remote communities.
Prospectively collected samples were split and screened conventionally and by ThinPrep at the Queensland Cytology Service.
Three hundred women having cervical smears taken by a Mobile Women's Health Service nurse or at the antenatal and sexual health clinics of a remote north Queensland community.
Number of Pap smears reported as unsatisfactory for evaluation and requiring a repeat smear request.
17.3% of conventionally prepared smears were technically unsatisfactory, compared with 6.3% prepared with ThinPrep. The overall rate of unsatisfactory smears was only 4.3% when both ThinPrep and conventional smears were assessed for a combined report.
A significant reduction in the proportion of unsatisfactory Pap smears is possible with the ThinPrep method. Targeted use of ThinPrep in communities with high rates of unsatisfactory smears may prove cost-effective.
评估使用薄层液基制片法（ThinPrep）降低偏远社区女性巴氏涂片检查（Pap涂片）不满意率的效果。
前瞻性收集的样本在昆士兰细胞学服务中心被分成两部分，分别采用传统方法和薄层液基制片法进行筛查。
300名由流动妇女健康服务护士或昆士兰北部偏远社区产前及性健康诊所采集宫颈涂片的女性。
报告为评估不满意且需要再次涂片检查的Pap涂片数量。
传统制片的涂片中有17.3%在技术上不满意，而采用薄层液基制片法的涂片这一比例为6.3%。当将薄层液基制片法和传统涂片结合评估以出具综合报告时，不满意涂片的总体比例仅为4.3%。
使用薄层液基制片法可显著降低Pap涂片不满意比例。在不满意涂片率高的社区有针对性地使用薄层液基制片法可能具有成本效益。
