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公共卫生机构在面向贫困人口的药物研发中能发挥什么作用?青蒿琥酯案例研究。

What role can public health institutions play in drug development for the poor? A case study of artesunate.

作者信息

Gomes M, Olliaro P, Folb P

机构信息

Special Programme for Research and Training in Tropical Diseases, TDR/WHO, Geneva, Switzerland.

出版信息

Med Trop (Mars). 1998;58(3 Suppl):97-100.

Abstract

Although the strategy of artesunate development was orchestrated from within WHO's Special Programme for Research and Training in Tropical Diseases, it relies heavily upon an alliance of scientist, laboratories, industry, regulators and ministries of health to ensure the public health outcome. This development strategy has transformed the way in which WHO does business, both within and outside the Organization. In essence, each and every player has rallied in the challenge to reduce the discrepancy between need and availability of a drug that can has the potential to reduce mortality form the disease.

摘要

尽管青蒿琥酯的研发策略是由世界卫生组织热带病研究和培训特别规划署内部精心策划的,但它在很大程度上依赖于科学家、实验室、产业界、监管机构和卫生部之间的联盟,以确保实现公共卫生成果。这一研发策略改变了世卫组织在本组织内外开展业务的方式。从本质上讲,每一个参与者都积极应对挑战,以缩小一种有可能降低该疾病死亡率的药物在需求和可及性之间的差距。

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