Fraenkel-Conrat H, Singer B
Virus Laboratory, University of California, Berkeley 94720-3206, USA.
Philos Trans R Soc Lond B Biol Sci. 1999 Mar 29;354(1383):583-6. doi: 10.1098/rstb.1999.0409.
This paper is a historical overview of the work done on the tobacco mosaic virus. The primary finding was that a virus is capable of reassembling itself from its component protein and RNA, and that only the RNA carries the genomic capability of the virus. This was followed by detailed studies of the chemical and biological properties of viral RNA.
本文是对烟草花叶病毒相关研究工作的历史综述。主要发现是病毒能够由其组成蛋白和RNA自我组装,并且只有RNA携带病毒的基因组能力。随后对病毒RNA的化学和生物学特性进行了详细研究。