Zimmern P, Leach G E, Yao J, Wolde-Tsadik G
Service d'Urologie, Kaiser Permanente Medical Center, Los Angeles, USA.
Prog Urol. 1999 Feb;9(1):37-44.
To define the changes in penile tumescence and rigidity in normally potent older men before a nerve-sparing radical retropubic prostatectomy (NS-RRP) and to establish a base-line for investigating erectile dysfunction in that age group.
75 patients used the Rigiscan for 2-3 nights before undergoing a NS-RRP procedure. Rigiscan data were analyzed visually using Kaneko & Bradley criteria, and by computerized analysis. The computerized data were compared to the patient self-evaluation of potency (questionnaire), patient's age (above and below 60 years old), peak cavernosal artery velocity measured by Duplex Doppler scanning, and to the visual analysis of the Rigiscan data.
55 of 75 men (73%) completed three sessions. 42 men had at least 2 normal sessions, and when compared to the 33 with abnormal visual tracings, only age was significantly characteristic (p < 0.05). Tip event rigidity (%) in < 60 year-old men was greater than in older men (p < 0.01). Nearly all men had erections lasting more than 2 minutes, while only 29 of 74 had 10 minutes erections with rigidity > 70%. The best correlation between visual and computerized analyses was noted in the group of 54 men who experienced > 70% rigidity for more than 2 minutes.
This large prospective series of potent older men studied by Rigiscan and other subjective and objective parameters helps establishing normative data in the diagnosis of erectile dysfunction. An important observation is clearly the lack of correlation between the patient's questionnaire or the Doppler findings and the Rigiscan data.
确定保留神经的耻骨后根治性前列腺切除术(NS-RRP)前正常性功能的老年男性阴茎勃起肿胀和硬度的变化,并为该年龄组勃起功能障碍的研究建立基线。
75例患者在接受NS-RRP手术前使用阴茎硬度测试仪(Rigiscan)2-3个晚上。使用金子&布拉德利标准对Rigiscan数据进行视觉分析,并进行计算机分析。将计算机分析数据与患者对性功能的自我评估(问卷)、患者年龄(60岁以上和以下)、经双功多普勒扫描测量的海绵体动脉峰值流速以及Rigiscan数据的视觉分析进行比较。
75名男性中有55名(73%)完成了三个阶段的测试。42名男性至少有2个正常阶段,与33名视觉记录异常的男性相比,只有年龄具有显著特征(p<0.05)。60岁以下男性的阴茎头部勃起硬度(%)大于老年男性(p<0.01)。几乎所有男性的勃起持续时间超过2分钟,而74名男性中只有29名勃起持续10分钟且硬度>70%。在54名硬度>70%持续超过2分钟的男性组中,视觉分析和计算机分析之间的相关性最佳。
通过Rigiscan以及其他主观和客观参数对这一大组有性功能的老年男性进行的前瞻性研究有助于建立勃起功能障碍诊断的规范数据。一个重要的观察结果显然是患者问卷或多普勒检查结果与Rigiscan数据之间缺乏相关性。