Yang Claire C, Porter Michael P, Penson David F
Department of Urology, University of Washington, Seattle, WA 98195-6510, USA.
BJU Int. 2006 Jul;98(1):105-9; discussion 109. doi: 10.1111/j.1464-410X.2006.06246.x.
To describe the relationship between the International Index of Erectile Function (IIEF) erectile domain score, and nocturnal penile tumescence and rigidity values measured by RigiScan (Timm Medical Technologies, Eden Prairie, MN).
In all, 73 men were evaluated with the IIEF and 2 nights of continuous penile monitoring with the RigiScan. Twenty-six men were evaluated before and after prostatectomy, for a total of 99 pairs of data points. We dichotomized the RigiScan results as 'adequate' (no erectile dysfunction, ED), or 'inadequate' (having ED), based on the 'best erectile event' over the 2 nights of monitoring. Two separate criteria for adequate erectile function were used, one of >70% rigidity for > or = 10 min, and the other >60% rigidity for > or = 10 min. The erectile domain score of the IIEF was calculated in the standard fashion.
Using both the 70% and the 60% rigidity criteria, there was a statistically significant association between the IIEF erectile domain scores and the RigiScan data (r = 0.27, P = 0.008 and r = 0.29, P = 0.003, respectively). However, the sensitivity of the IIEF to predict ED based on RigiScan results using the 70% rigidity criteria was 68.9%, and the specificity was 57.1%. When the IIEF was used as a continuous predictor of RigiScan results, the area under the receiver-operating characteristic (ROC) curve was 0.66. Using the 60% criteria, the sensitivity was 55.8% and the specificity was 73.2%; the area under the ROC curve was 0.72.
IIEF erectile domain scores and nocturnal penile tumescence and rigidity measurements are weakly associated, and the clinical utility of one test to predict the other is limited. However, because of the differences in the measured outcomes (perception of erectile function vs physiological capacity), a weak association does not disqualify either test's individual utility.
描述国际勃起功能指数(IIEF)勃起功能领域评分与通过RigiScan(Timm医疗技术公司,明尼苏达州伊甸草原)测量的夜间阴茎肿胀和硬度值之间的关系。
共有73名男性接受了IIEF评估,并使用RigiScan进行了连续两晚的阴茎监测。26名男性在前列腺切除术前和术后接受了评估,总共获得99对数据点。根据监测两晚期间的“最佳勃起事件”,我们将RigiScan结果分为“充分”(无勃起功能障碍,ED)或“不充分”(存在ED)。使用了两种不同的充分勃起功能标准,一种是硬度>70%持续≥10分钟,另一种是硬度>60%持续≥10分钟。IIEF的勃起功能领域评分采用标准方式计算。
使用70%和60%硬度标准时,IIEF勃起功能领域评分与RigiScan数据之间均存在统计学显著关联(r分别为0.27,P = 0.008和r = 0.29,P = 0.003)。然而,基于70%硬度标准,IIEF预测基于RigiScan结果的ED的敏感性为68.9%,特异性为57.1%。当将IIEF用作RigiScan结果的连续预测指标时,受试者操作特征(ROC)曲线下面积为0.66。使用60%标准时,敏感性为55.8%,特异性为73.2%;ROC曲线下面积为0.72。
IIEF勃起功能领域评分与夜间阴茎肿胀和硬度测量之间存在弱关联,一种检测方法预测另一种检测方法的临床效用有限。然而,由于测量结果不同(勃起功能的感知与生理能力),弱关联并不影响任何一种检测方法的个体效用。