Saporta F, Salomon L, Amsellem D, Patard J J, Hozneck A, Colombel M, Chopin D, Abbou C
Service d'Urologie, CHU Henri Mondor, Créteil, France.
Prog Urol. 1999 Feb;9(1):47-51.
Complications of the ureterovesical anastomosis after renal transplantation are the most frequent surgical complications, estimated to occur in 3 to 20% of cases, depending on the series. Various techniques have been used to treat anastomotic leaks, stenoses or reflux. We present the results of pyeloureterostomy using the recipient's own ureter.
520 cadaver kidney renal transplantations were performed between 1988 and 1996. The ureterovesical anastomosis was performed according to the Lich Gregoir technique. Sixteen recipients (3%) developed an anastomotic complication: 9 stenoses (1.7%), 6 leaks (1.1%), 1 reflux (0.2%). The mean age of the donor was 37 years and the mean cold ischaemia time was 30 hours. There were 8 right kidneys and 8 left kidneys, transplanted in the right iliac fossa in 11 cases and left iliac fossa in 5 cases. The mean age of the recipients was 42 years, and they were transplanted for nephropathy in 15 cases and uropathy in 1 case. Surgical revision was performed 1 month after transplantation for anastomotic leaks and after 14 months for stenoses. In every case, the native ureter was identified by a ureteric catheter via a midline incision except for 3 cases of early anastomotic leak (< 3 days). The native ureter was sectioned without associated ipsilateral nephrectomy then anastomosed to the renal pelvis of the transplant, which was then drained by a Gil-Vernet catheter (10 cases) or ureteric stent (6 cases).
One transplant was lost on D1 due to renal vein thrombosis. One nephrostomy was inserted on D2 due to obstruction of the ureteric stent. Follow-up pyelography on D15 was normal in every case. The mean follow-up was 2.5 years (2.9 years for anastomotic leaks, 2.2 for stenoses, 3.6 for reflux). One patient died with a functional renal transplant 3 years after the operation and one transplant was lost due to chronic rejection 4 years later. No complications involving the native kidney ipsilateral to the anastomosis were observed and there were no repeated ureteric complications. Mean creatinine 3 years after the operation was 141 mumol/l.
Pyeloureterostomy is a reliable technique in the case of complications of the ureterovesical anastomosis. Pyeloureterostomy via a midline incision allowed one-stage definitive treatment of all anastomotic complications of the ureterovesical anastomosis with a low morbidity.
肾移植术后输尿管膀胱吻合口并发症是最常见的手术并发症,据不同系列报道,其发生率估计在3%至20%之间。已采用多种技术治疗吻合口漏、狭窄或反流。我们展示了使用受者自身输尿管进行肾盂输尿管吻合术的结果。
1988年至1996年间进行了520例尸体肾肾移植手术。输尿管膀胱吻合术采用利希·格雷戈尔技术。16例受者(3%)出现吻合口并发症:9例狭窄(1.7%),6例漏(1.1%),1例反流(0.2%)。供者平均年龄37岁,平均冷缺血时间30小时。有8个右肾和8个左肾,11例移植于右髂窝,5例移植于左髂窝。受者平均年龄42岁,其中15例因肾病接受移植,1例因尿路病接受移植。吻合口漏于移植后1个月进行手术修复,狭窄于14个月后进行修复。除3例早期吻合口漏(<3天)外,均通过输尿管导管经中线切口识别自体输尿管。在未行同侧肾切除术的情况下切断自体输尿管,然后将其与移植肾的肾盂吻合,再通过吉尔 - 韦尔内导管(10例)或输尿管支架(6例)引流。
1例移植肾因肾静脉血栓形成于术后第1天丢失。1例因输尿管支架阻塞于术后第2天置入肾造瘘管。术后第15天的随访肾盂造影检查结果均正常。平均随访时间为2.5年(吻合口漏为2.9年,狭窄为2.2年,反流为3.6年)。1例患者术后3年因功能性肾移植死亡,1例移植肾4年后因慢性排斥反应丢失。未观察到吻合口同侧自体肾的并发症,也未出现输尿管并发症复发。术后3年的平均肌酐水平为141μmol/L。
对于输尿管膀胱吻合口并发症,肾盂输尿管吻合术是一种可靠的技术。经中线切口进行肾盂输尿管吻合术可对输尿管膀胱吻合口的所有吻合口并发症进行一期确定性治疗,且发病率较低。