Nagy J
Nephrological Center and Second Department of Medicine, University Medical School of Pécs, Hungary.
Am J Nephrol. 1999;19(2):346-9. doi: 10.1159/000013474.
In January 1902 at the Vienna Medical Society Meeting, the surgeon Emerich Ullmann reported the first case of renal autotransplantation performed in the neck of a dog. In the same year, he presented the first xenotransplantation of the kidney (a goat with a dog's kidney). These publications immediately had a great impact on the medical word. After his failed attempt to transplant a pig's kidney into a young uraemic woman he stopped his research in this field in order to devote himself to other lines of surgical research. However, his idea survived him, because, nowadays, nearly 100 years later, pigs appear to be the most suitable donors for human renal xenotransplantation. Ullmann was born in Pécs, Hungary, on February 23, 1861. After a distinguished undergraduate career in 1878 his father (being also a medical doctor) sent him to study medicine at the world-famous Vienna Medical School. He graduated in 1884 and was immediately invited to the Surgical Department where Billroth worked. Next year, because of his interest in bacteriology he visited Pasteur in Paris and successfully volunteered to serve as a healthy subject to prove the effectiveness of Pasteur's antisera against rabies. Although Ullmann did not succeed in doing a human transplantation he gave birth to the era of the organ transplantation, stimulated vascular surgery and the development of transplantation immunology.
1902年1月,在维也纳医学协会会议上,外科医生埃默里希·乌尔曼报告了首例在狗颈部进行的肾自体移植手术。同年,他进行了首例肾脏异种移植(将狗肾移植到山羊体内)。这些出版物立即在医学界产生了巨大影响。在他将猪肾移植到一名年轻尿毒症妇女的尝试失败后,他停止了在该领域的研究,转而投身于其他外科研究领域。然而,他的想法在他身后得以延续,因为在近100年后的今天,猪似乎是人类肾脏异种移植最合适的供体。乌尔曼于1861年2月23日出生在匈牙利的佩奇。1878年,他在本科阶段成绩优异后,他的父亲(也是一名医生)送他到世界著名的维也纳医学院学习医学。他于1884年毕业,并立即被邀请到比尔罗特所在的外科工作。次年,由于他对细菌学的兴趣,他前往巴黎拜访了巴斯德,并成功自愿作为健康受试者,以证明巴斯德抗狂犬病血清的有效性。尽管乌尔曼没有成功进行人体移植,但他开创了器官移植的时代,推动了血管外科和移植免疫学的发展。