Vince J D
Department of Clinical Sciences, University of Papua New Guinea, Port Moresby, Papua New Guinea.
P N G Med J. 1996 Dec;39(4):329-37.
In the last decade advances in knowledge of the aetiology and pathogenesis of asthma, and the availability of metered-dose inhalers and nebulisers, has led to a change in emphasis in both the preventive and curative aspects of the management of children with asthma. Metered-dose inhalers are available in Papua New Guinea, and can be used successfully, with spacing devices, even in children less than 2 years of age. Inhaled beta-sympathomimetics, now widely available and relatively inexpensive, may be all that is required for the majority of children with infrequent episodic asthma. For those with frequent episodic and chronic asthma, preventive therapy with inhaled steroids is available and should be given wherever practicable. In the management of acute severe asthma inhaled beta-sympathomimetics should be combined with a short course of oral or parenteral steroids (covered with isoniazid in areas where tuberculosis is prevalent). Whilst asthma classically presents with wheeze, medical personnel should be aware of its other presentations. It is possible, and should be the aim, to achieve a very high level of control for the majority of asthmatic children using currently available therapy.
在过去十年中,哮喘病因学和发病机制方面的知识进展,以及定量吸入器和雾化器的出现,使得哮喘患儿管理的预防和治疗重点发生了变化。巴布亚新几内亚有定量吸入器,即使是2岁以下的儿童,使用间隔装置也能成功使用。吸入型β-拟交感神经药现在广泛可得且相对便宜,对于大多数偶发性哮喘儿童来说,可能这就是所需的全部治疗。对于那些频繁发作性和慢性哮喘患儿,可使用吸入性类固醇进行预防性治疗,且在可行的情况下都应给予。在急性重症哮喘的管理中,吸入型β-拟交感神经药应与短期口服或胃肠外类固醇联合使用(在结核病流行地区用异烟肼预防)。虽然哮喘典型表现为喘息,但医务人员应了解其其他表现形式。利用现有治疗方法,使大多数哮喘儿童实现非常高水平的控制是可能的,也应该是目标。