Gisselbrecht M
Service de Médecine Interne 1, Hôpital Laënnec, Paris, France.
Pathol Biol (Paris). 1999 Mar;47(3):245-7.
Vasculitis is among the dysimmunity-mediated disorders seen in patients infected with the human immunodeficiency virus (HIV). Several cases have been reported. The central and peripheral nervous systems were the main targets, although many other organs may be involved. There were wide variations in clinical presentation, clinico-pathologic patterns, and the stage of the HIV infection at vasculitis onset. Causes included drugs and infections, particularly some opportunistic infections. In some cases, the vasculitis seemed to be directly due to the HIV. The etiopathogenesis remains unclear and the treatment unstandardized. Four cases of systemic vasculitis in HIV-infected patients are reported herein. All four patients received the treatment recommended for hepatitis B virus-related polyarteritis nodosa, namely plasma exchange and antiretroviral drugs.
血管炎是人类免疫缺陷病毒（HIV）感染患者中出现的免疫失调介导的疾病之一。已有多例相关报道。中枢神经系统和周围神经系统是主要受累部位，不过许多其他器官也可能被累及。血管炎发作时，临床表现、临床病理模式以及HIV感染阶段存在很大差异。病因包括药物和感染，尤其是一些机会性感染。在某些情况下，血管炎似乎直接由HIV引起。其发病机制仍不清楚，治疗也未标准化。本文报告了4例HIV感染患者的系统性血管炎病例。所有4例患者均接受了针对乙型肝炎病毒相关性结节性多动脉炎推荐的治疗，即血浆置换和抗逆转录病毒药物。
