Kanda M, Yasuda S, Goto Y, Sumida H, Baba T, Noguchi T, Nonogi H
Department of Internal Medicine, National Cardiovascular Center, Suita, Osaka, Japan.
Am J Cardiol. 1999 Apr 15;83(8):1274-7, A9. doi: 10.1016/s0002-9149(99)00073-9.
We examined the diuretic effects of phosphodiesterase inhibitors in heart failure patients with and without renal failure. We found that, despite the improvement in central hemodynamics, phosphodiesterase inhibitors do not necessarily facilitate diuresis in heart failure in patients with concomitant renal failure.
我们研究了磷酸二酯酶抑制剂对伴有和不伴有肾功能衰竭的心力衰竭患者的利尿作用。我们发现，尽管中心血流动力学有所改善，但磷酸二酯酶抑制剂并不一定能促进伴有肾功能衰竭的心力衰竭患者的利尿。
