Tashev Kh R, Blagov I N
Khirurgiia (Mosk). 1999(3):37-9.
Taking into account the processes of deposition of toxins in conditions of disturbed microcirculation in syndrome of endogenous intoxication (SEI) in patients with acute diffuse peritonitis (ADP) of various origin, the authors consider determination of concentration of the medium-molecular (MM) toxins only in blood plasma rather uninformative. They suggest simultaneous determination of them in various biological substanees of patients with ADP (blood from various vascular beds, peritoneal exudate, hymus, urine), which makes it possible to reveal basic stages of kinetics of the medium-size molecules in extracorporeal detoxication.
考虑到各种病因的急性弥漫性腹膜炎（ADP）患者内源性中毒综合征（SEI）微循环紊乱情况下毒素的沉积过程，作者认为仅测定血浆中中分子（MM）毒素的浓度信息量不足。他们建议同时测定ADP患者的各种生物物质（来自不同血管床的血液、腹腔渗出液、胸腺、尿液）中的中分子毒素，这有助于揭示体外解毒过程中中分子的基本动力学阶段。
