Chuchro P, Cichowska B, Dobkowska E, Gronek I, Mierzwa K, Sawiec P, Sznajd J
SKN Pulmonologiczno-Aiergologiczne, Polsko-Amerykańskiego Instytutu Pediatrii, Uniwersytetu Jagiellońskiego w Krakowie.
Przegl Lek. 1998;55(11):586-90.
The aim of the study was to evaluate the relationship between h.d.m. allergy and incidence of respiratory tract infections in children with episodic, mild and moderate asthma. 32 children with bronchial asthma being followed up at the I. Department of Children Diseases P.A.I.P. CMUJ in Cracow were included into the study. The positive skin prick test (SPT) with H.D.M. allergens was confirmed in 18 children. The negative SPT allergens were observed in 14 patients. All patients were examinated by the retrospective inquiry which included the degree of asthma, severity of therapy schedule and incidence of acute respiratory tract infections during the last 6 months. The anthropometric measurement (length, weight, body mass index, thorax circumference) and spirometric parameters with physical examination challenge were introduced. The mean number of infections in group of patients sensitive to H.D.M. was 6.8; in non sensitive group-4.6. There was no significant difference in incidence of acute respiratory tract infections between both groups. It seems likely that small number of patients may influence the statistics. To verify the results, prospective observation of wider group of patients is planned in forthcoming winter.
该研究的目的是评估患有发作性、轻度和中度哮喘的儿童中屋尘螨过敏与呼吸道感染发生率之间的关系。克拉科夫雅盖隆大学医学院儿科学系第一科室正在随访的32名支气管哮喘儿童被纳入该研究。18名儿童经屋尘螨过敏原皮肤点刺试验（SPT）呈阳性。14名患者的SPT过敏原检测为阴性。所有患者均通过回顾性询问进行检查，内容包括哮喘程度、治疗方案的严重程度以及过去6个月内急性呼吸道感染的发生率。引入了人体测量指标（身长、体重、体重指数、胸围）以及肺功能参数和体格检查激发试验。对屋尘螨敏感的患者组平均感染次数为6.8次；非敏感组为4.6次。两组之间急性呼吸道感染的发生率没有显著差异。可能是患者数量较少影响了统计结果。为了验证结果，计划在即将到来的冬季对更广泛的患者群体进行前瞻性观察。
