接种途径对北京鸭（绿头鸭）中猛禽多杀性巴氏杆菌分离株毒力的影响

The effect of route of inoculation on the virulence of raptorial Pasteurella multocida isolates in Pekin ducks (Anas platyrhynchos).

作者信息

Pehlivanoglu F, Morishita T Y, Aye P P, Porter R E, Angrick E J, Harr B S, Nersessian B

机构信息

Department of Veterinary Preventive Medicine, Ohio State University, Columbus 43210-1092, USA.

出版信息

Avian Dis. 1999 Jan-Mar;43(1):116-21.

PMID:10216767

Abstract

The purpose of this study was to determine the virulence of raptorial Pasteurella multocida for ducks and the effect of various routes of inoculation on virulence. Four-week-old Pekin ducks (Anas platyrhynchos) were challenged with one of three raptorial isolates (RTHA-2, RTHA-4, or WESO-1) by one of five inoculation routes (intranasal, intraocular, intravenous, oral, and subcutaneous). Ducks were monitored daily for mortality until 2 wk postchallenge. Results indicated that the intravenous route caused the most mortality for all isolates and that significant variation existed in the virulence among the sources of P. multocida, with WESO-1 causing the least mortality of the isolates tested.

摘要

本研究的目的是确定掠食性多杀性巴氏杆菌对鸭的毒力以及不同接种途径对毒力的影响。用三种掠食性分离株（RTHA - 2、RTHA - 4或WESO - 1）之一，通过五种接种途径（鼻内、眼内、静脉内、口服和皮下）对4周龄的北京鸭（绿头鸭）进行攻毒。每天监测鸭的死亡率，直至攻毒后2周。结果表明，静脉内接种途径导致所有分离株造成的死亡最多，并且多杀性巴氏杆菌不同来源之间的毒力存在显著差异，其中WESO - 1在所测试的分离株中导致的死亡率最低。