Hayakawa T, Iida Y, Tsuge H
Department of Food Science, Faculty of Agriculture, Gifu University, Japan.
Int J Vitam Nutr Res. 1999 Mar;69(2):106-12. doi: 10.1024/0300-9831.69.2.106.
To investigate how dietary fiber in the diet affects vitamin B-6 nutriture of rats which have been deprived of vitamin B-6, rats were made vitamin B-6-deficient by feeding a vitamin B-6-deficient 70% casein diet. They were fed 2% cellulose powder-based vitamin B-6-deficient diets supplemented with 3% of additional dietary fiber sources (agar, konjac mannan, pectin and cellulose powder) for subsequent 18 days. Vitamin B-6 status was evaluated according to several biological criteria (weight gain, urinary excretion of xanthurenic acid after tryptophan loading, plasma pyridoxal 5'-phosphate, apparent pyridoxal 5'-phosphate-saturation of liver kynureninase, urinary excretion of 4-pyridoxic acid and fecal output of vitamin B-6). Vitamin B-6 status evaluated by these criteria was considerably improved in the konjac mannan-fed group, when compared with the respective data of the vitamin B-6 supplemented group. The relative mean effect of the konjac mannan diet was about 40% of the vitamin B-6 supplemented diet. In conclusion, konjac mannan was effective for improving the vitamin B-6 nutritional state in vitamin B-6-deprived rats.
为了研究饮食中的膳食纤维如何影响已缺乏维生素B-6的大鼠的维生素B-6营养状况，通过喂食缺乏维生素B-6的70%酪蛋白饮食使大鼠维生素B-6缺乏。随后18天，给它们喂食以2%纤维素粉为基础的缺乏维生素B-6的饮食，并补充3%的其他膳食纤维来源（琼脂、魔芋甘露聚糖、果胶和纤维素粉）。根据几个生物学标准（体重增加、色氨酸负荷后尿中黄尿酸的排泄、血浆磷酸吡哆醛、肝脏犬尿氨酸酶的表观磷酸吡哆醛饱和度、尿中4-吡哆酸的排泄以及维生素B-6的粪便排出量）评估维生素B-6状况。与补充维生素B-6组的相应数据相比，魔芋甘露聚糖喂养组通过这些标准评估的维生素B-6状况有显著改善。魔芋甘露聚糖饮食的相对平均效果约为补充维生素B-6饮食的40%。总之，魔芋甘露聚糖对改善维生素B-6缺乏大鼠的维生素B-6营养状况有效。
