Ware G T, Haik B G, Morris W R
Department of Ophthalmology, University of Tennessee, Memphis 38163, USA.
Am J Ophthalmol. 1999 Apr;127(4):460-1. doi: 10.1016/s0002-9394(98)00357-2.
To report a case of metastatic renal cell carcinoma with involvement of the iris and bulbar conjunctiva.
Case report. A 70-year-old man without known systemic disease developed an iris mass in his left eye. Iridocyclectomy was performed to remove the iris mass.
Histopathologically, the iris mass was consistent with metastatic renal cell carcinoma. Further evaluation disclosed a mass of the left kidney. The patient underwent a left nephrectomy and was found to have renal cell carcinoma, with focal penetration into the renal capsule. One month after the nephrectomy, he developed a highly vascular nodule of the left bulbar conjunctiva. An excisional biopsy was performed, and histopathology disclosed an additional focus of renal cell carcinoma.
Iris and conjunctival involvement may be a clinical manifestation of renal cell carcinoma. Renal cell carcinoma should be considered in the differential diagnosis of a fleshy, vascular iris and a conjunctival nodule.
报告一例伴有虹膜和球结膜受累的转移性肾细胞癌病例。
病例报告。一名70岁无已知全身性疾病的男性左眼出现虹膜肿物。行虹膜睫状体切除术以切除虹膜肿物。
组织病理学检查显示，虹膜肿物符合转移性肾细胞癌。进一步评估发现左肾有肿物。患者接受了左肾切除术，病理显示为肾细胞癌，局部侵犯肾包膜。肾切除术后1个月，他左眼球结膜出现一个高血管化结节。进行了切除活检，组织病理学检查发现另一个肾细胞癌病灶。
虹膜和结膜受累可能是肾细胞癌的一种临床表现。在鉴别诊断肉质、血管性虹膜和结膜结节时应考虑肾细胞癌。
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