Settineri N, Pergolizzi S, Raffaele L, Maisano R, Russi E G
Satellite Unit of Biomedical Technology (Radiobiomedical Area), IST-Genova, Italy.
Int J Radiat Oncol Biol Phys. 1999 Apr 1;44(1):221-6. doi: 10.1016/s0360-3016(98)00480-5.
An overall check of the whole dosimetry procedure by intracavitary in vivo dosimetry, using n-type silicon diode dosimeter, was performed during 6-MV x-ray irradiation of the vaginal vault. The dose delivered to the isocenter by all treatment fields was evaluated.
The diode dosimeter was calibrated against an ion chamber and tissue maximum ratio, field size factor, SSD factor, and temperature dependence studies were performed. Diode system accuracy, linearity, and reproducibility were also tested. Patients' dose data were collected and comparision was made with respect to treatment-planning dose calculations. Ten patients with cervical cancer and endometrial cancer were treated with surgery and irradiation. During the boost to the vaginal vault, a diode was inserted by an intravaginal device and the vaginal vault was the isocenter of the four fields. The field size generally was not larger than 10 x 10 cm2.
Diode-measured "tissue maximum ratio" agreed to within 1% with those measured with an ion chamber in field from 7 x 7 to 10 x 10 cm2. The diode also exhibited a temperature dependence of 0.1% degrees C(-1). For 10 patients treated with a 6-MV beam, the agreement with treatment-planning dose calculations was shown to be better than +/-4%.
The good accuracy and reproducibility of the diode system shows that determination of the dose at isocenter, for patients treated in the pelvic region, can be performed with n-type diodes accurately. On the other hand, in the vaginal vault boost, external-beam radiotherapy is delivered accurately and in vivo dosimetry is really not indicated.
在阴道穹窿部的6兆伏X射线照射期间,使用n型硅二极管剂量仪通过腔内体内剂量测定法对整个剂量测定程序进行全面检查。评估所有治疗野传递至等中心的剂量。
将二极管剂量仪相对于电离室进行校准,并进行组织最大剂量比、射野大小因子、源皮距因子和温度依赖性研究。还测试了二极管系统的准确性、线性和可重复性。收集患者的剂量数据,并与治疗计划剂量计算结果进行比较。10例宫颈癌和子宫内膜癌患者接受了手术和放疗。在对阴道穹窿部进行加量照射时,通过阴道内装置插入一个二极管,阴道穹窿部为四个野的等中心。射野大小一般不大于10×10平方厘米。
在7×7至10×10平方厘米的射野中,二极管测量的“组织最大剂量比”与电离室测量的结果相差在1%以内。二极管的温度依赖性也表现为每摄氏度0.1%。对于10例接受6兆伏射线治疗的患者,与治疗计划剂量计算结果的一致性显示优于±4%。
二极管系统良好的准确性和可重复性表明,对于盆腔区域接受治疗的患者,使用n型二极管可以准确测定等中心处的剂量。另一方面,在阴道穹窿部加量照射中,外照射放疗传递准确,体内剂量测定实际上并无必要。