Milner R, Adzick N S
The Center for Fetal Diagnosis and Treatment, The Children's Hospital of Philadelphia, PA 19104, USA.
Curr Opin Obstet Gynecol. 1999 Apr;11(2):177-83. doi: 10.1097/00001703-199904000-00010.
Advances in prenatal imaging modalities such as ultrasound and magnetic resonance imaging have permitted the more frequent and accurate diagnosis of congenital malformations. Fetal surgical intervention has been reserved for those malformations that lead to fetal demise or are life-threatening in the neonatal period. We review the current indications for intervention in fetuses diagnosed with congenital lung lesions, congenital diaphragmatic hernia, sacrococcygeal teratoma, and obstructing airway lesions. A discussion of the recent interest in the fetal repair of severe myelomeningocele is also included.
超声和磁共振成像等产前成像技术的进步使得先天性畸形的诊断更加频繁和准确。胎儿外科干预一直用于那些会导致胎儿死亡或在新生儿期危及生命的畸形。我们回顾了目前对诊断为先天性肺部病变、先天性膈疝、骶尾部畸胎瘤和气道阻塞性病变的胎儿进行干预的指征。本文还讨论了近期对严重脊髓脊膜膨出胎儿修复的关注。