Hosie S, Wollmann C, Neff W, Holland-Cunz S
Kinderchirurgische Universitätsklinik, Klinikum Mannheim, Fakultät für Klinische Medizin Mannheim der Universität Heidelberg.
Chirurg. 2005 Aug;76(8):757-64. doi: 10.1007/s00104-005-1065-3.
Fetal surgery is a newly evolving multidisciplinary medical field, being performed in specialized centers. It deals with the treatment of selected fetuses with congenital anomalies that cause high morbidity and mortality. The aim of the surgical treatment is to avoid the development of progressive and eventually irreversible damage at birth. Examples of entities treated are obstructive uropathy leading to renal insufficiency, lung hypoplasia in severe congenital diaphragmatic hernia, severe congenital cystic adenomatoid malformation of the lung, and sacrococcygeal teratoma. This review describes principles of fetal surgery, physiopathologic processes of some of the anomalies treated in this way, and diagnostic and therapeutic approaches. Recently published results are presented and discussed.
胎儿外科是一个新兴的多学科医学领域，在专门的中心开展。它致力于治疗某些患有先天性异常的胎儿，这些异常会导致高发病率和死亡率。外科治疗的目的是避免出生时出现进行性且最终不可逆转的损害。接受治疗的病症包括导致肾功能不全的梗阻性尿路病、严重先天性膈疝中的肺发育不全、严重先天性肺囊性腺瘤样畸形以及骶尾部畸胎瘤。本综述描述了胎儿外科的原则、以这种方式治疗的一些异常的生理病理过程以及诊断和治疗方法。还展示并讨论了最近发表的结果。
