Graf M, Blaeker H, Schnabel P, Serpi M, Ulmer H E, Otto H F
Institute of Pathology, University of Heidelberg, Germany.
Pathol Res Pract. 1999;195(3):193-7. doi: 10.1016/S0344-0338(99)80034-X.
We report about a two and a half year old girl with a primary yolk sac tumor (YST) of the heart, located in the interventricular septum. The girl was admitted to the hospital with a systolic cardiac murmur. Echocardiography revealed a smoothly surfaced tumor which based on the interventricular septum below the aortic valve and filled out more than half of the left ventricular cavity. Diagnosis of a yolk sac tumor was established on a frozen section of a biopsy taken at surgery and confirmed by the examination of the resected material. Excessively elevated serum alpha-fetoprotein (AFP) levels contributed to this diagnosis. Follow up examinations of the patient including computed tomography (CT) of head, thorax and abdomen, did not indicate an extracardiac tumor manifestation. We found no previous report of a primary intracardial yolk sac tumor in the literature.
我们报告了一名两岁半的女孩，患有原发性心脏卵黄囊瘤（YST），位于室间隔。该女孩因收缩期心脏杂音入院。超声心动图显示一个表面光滑的肿瘤，位于主动脉瓣下方的室间隔上，占据了左心室腔的一半以上。手术活检的冰冻切片确诊为卵黄囊瘤，并经切除材料检查证实。血清甲胎蛋白（AFP）水平异常升高有助于该诊断。对患者进行的包括头部、胸部和腹部计算机断层扫描（CT）在内的后续检查未显示心外肿瘤表现。我们在文献中未发现原发性心内卵黄囊瘤的先前报告。
