Alhumidi Ahmed, Al Shaikh Safa, Alhammadi Abdullah
Department of Pathology, King Khalid University Hospital, King Saud University Riyadh, Saudi Arabia.
Int J Clin Exp Pathol. 2015 Feb 1;8(2):2183-5. eCollection 2015.
Malignant germ-cell tumors (MGCT) are rare tumors of childhood accounting for less than 3% of pediatric malignancies. Yolk sac (endodermal sinus) tumor is one of the malignant germ cell tumor that usually involves the gonads (ovaries and testes). Its occurrence in the vagina is extremely rare. We report a 6-months old girl presented with a vaginal mass diagnosed as a yolk sac tumor. This diagnosis is confirmed by histopathologic examination, immunehistochemical studies as well as elevated serum alpha fetoprotein (AFP).
恶性生殖细胞肿瘤(MGCT)是儿童期罕见肿瘤,占儿童恶性肿瘤的比例不到3%。卵黄囊(内胚窦)瘤是恶性生殖细胞肿瘤之一,通常累及性腺(卵巢和睾丸)。其发生于阴道极为罕见。我们报告一名6个月大的女童,因阴道肿物就诊,诊断为卵黄囊瘤。这一诊断通过组织病理学检查、免疫组织化学研究以及血清甲胎蛋白(AFP)升高得以证实。