Ravera M, Reggiori A, Agliata A M, Rocco R P
Regional Teaching Hospital, Hoima, Uganda.
Emerg Infect Dis. 1999 Mar-Apr;5(2):274-7. doi: 10.3201/eid0502.990214.
A randomized cross-over clinical and endoscopic evaluation of 85 Ugandan patients showed that esophageal candidiasis in AIDS patients with oral candidiasis could be managed without endoscopy and biopsies. Oral lesions, especially when accompanied by esophageal symptoms, were sufficient for diagnosis. Miconazole was more effective than nystatin in treating esophageal candidiasis and could be a valid alternative to more expensive azolic drugs in developing countries.
对85名乌干达患者进行的随机交叉临床和内镜评估表明,患有口腔念珠菌病的艾滋病患者的食管念珠菌病无需通过内镜检查和活检即可得到治疗。口腔病变,尤其是伴有食管症状时,足以用于诊断。在治疗食管念珠菌病方面,咪康唑比制霉菌素更有效,在发展中国家,它可以作为更昂贵的唑类药物的有效替代药物。