Ann Intern Med. 1978 Dec;89(6):949-50.
Meningococcal disease is endemic in the United States, and sulfonamide-sensitive serogroup B strains currently cause most cases. More than two thirds of all cases occur in persons less than 20 years old. Three meningococcal polysaccharide vaccines are licensed for selective use in the United States: monovalent A, monovalent C, and bivalent A-C. This recommendation describes indications for their use, with particular attention to primary immunization, and use in pregnancy and in epidemic control.
脑膜炎球菌病在美国呈地方性流行,目前大多数病例由对磺胺类药物敏感的B群菌株引起。所有病例中超过三分之二发生在20岁以下的人群中。三种脑膜炎球菌多糖疫苗已获许可在美国选择性使用:单价A疫苗、单价C疫苗和双价A-C疫苗。本建议描述了它们的使用指征,特别关注初次免疫、孕期使用及疫情控制方面的情况。