MMWR Morb Mortal Wkly Rep. 1998 Oct 9;47(39):833-7.
Since 1992, Neisseria meningitidis serogroup B strains have caused several community- and school-based outbreaks in the United States. Response to such outbreaks is difficult because no serogroup B vaccine is licensed currently for use in the United States, and mass chemoprophylaxis has been evaluated only in restricted settings. This report describes the use of mass prophylaxis to control outbreaks of serogroup B meningococcal disease in Florida in two unusual settings: a hotel resort and a nursing home.
自1992年以来,B群脑膜炎奈瑟菌菌株在美国引发了多起社区和学校疫情。应对此类疫情颇具难度,因为目前尚无B群疫苗获美国许可使用,且大规模化学预防仅在有限环境中进行过评估。本报告描述了在佛罗里达州两个不同寻常的场所——一个度假酒店和一家疗养院——使用大规模预防措施来控制B群脑膜炎球菌病疫情的情况。