Dowd J E, Glasunov I S, Jaksić Z, Kesić B, Ray D, Steinberger C, Stromberg J, Vuletić S
Cor Vasa. 1976;18(4):277-86.
A procedure for recruitment of a trial cohort from a demographically defined population is described. Provision was made by means of a prescreening survey to determine demographic and attitudinal characteristics in the group invited to screening before the invitation was extended, thus providing information on non-participants as well as participants. Men who satisfied the criteria for borderline levels of one or more of the three risk factors on at least two of possible three occasions were invited to participate in a radomized multifactor treatment trial either being treated by medication for the appropriate risk factor [or factors], or observed during the same intervals in the same fashion as those treated. During follow-up attempts were made to measure adherence to the prescribed medication.
本文描述了一种从特定人口统计学定义人群中招募试验队列的程序。通过预筛查调查来确定在邀请发出前被邀请参加筛查的人群的人口统计学和态度特征,从而提供关于未参与者以及参与者的信息。在可能的三次机会中,至少两次满足三个风险因素中一个或多个临界水平标准的男性被邀请参加一项随机多因素治疗试验,要么接受针对适当风险因素的药物治疗,要么在相同间隔内以与接受治疗者相同的方式进行观察。在随访期间,尝试测量对规定药物的依从性。