Shih M H, Sheu M M, Chen H Y, Lin S R
Department of Ophthalmology, College of Medicine, National Cheng-Kung University, Tainan, Republic of China.
Kaohsiung J Med Sci. 1999 Mar;15(3):171-4.
We report the first case of an ocular fungal infection caused by Candida utilis in a 72-year-old woman. Although candidiasis is the most common opportunistic fungal infection in humans, C. utilis had not been associated with human morbidity until two cases of fungemia were reported in 1988 and 1993. The clinical features exhibited typical feather-like infiltration at the ulceration margin of this case. After treatment with topical fluconazole and amphotericin-B, the ulceration healed within 3 weeks. The patient underwent penetrating keratoplasty and regained useful vision. We concluded that C. utilis is a new corneal pathogen and should be included in the differential list of mycotic keratitis.
我们报告了首例由产朊假丝酵母引起的眼部真菌感染病例,患者为一名72岁女性。虽然念珠菌病是人类最常见的机会性真菌感染,但直到1988年和1993年分别报告了两例真菌血症病例后,产朊假丝酵母才与人类发病相关。该病例的临床特征表现为溃疡边缘典型的羽毛状浸润。经局部使用氟康唑和两性霉素B治疗后,溃疡在3周内愈合。患者接受了穿透性角膜移植术并恢复了有用视力。我们得出结论,产朊假丝酵母是一种新的角膜病原体,应列入真菌性角膜炎的鉴别诊断清单。