苯丙酮尿症孕产妇资源母亲项目
The Resource Mothers Program for Maternal Phenylketonuria.
作者信息
St James P S, Shapiro E, Waisbren S E
机构信息
Psychology Department, University of Massachusetts at Boston, USA.
出版信息
Am J Public Health. 1999 May;89(5):762-4. doi: 10.2105/ajph.89.5.762.
OBJECTIVES
The purpose of this study was to measure the effectiveness of resource mothers in reducing adverse consequences of maternal phenylketonuria.
METHODS
Nineteen pregnancies in the resource mothers group were compared with 64 pregnancies in phenylketonuric women without resource mothers. Weeks to metabolic control and offspring outcome were measured.
RESULTS
Mean number of weeks to metabolic control was 8.5 (SE = 2.2) in the resource mothers group, as compared with 16.1 (SE = 1.7) in the comparison group. Infants of women in the resource mothers group had larger birth head circumferences and higher developmental quotients.
CONCLUSIONS
The resource mothers program described here improves metabolic control in pregnant women with phenylketonuria.
目的
本研究旨在衡量资源母亲在减少母体苯丙酮尿症不良后果方面的有效性。
方法
将资源母亲组的19次妊娠与无资源母亲的苯丙酮尿症女性的64次妊娠进行比较。测量达到代谢控制的周数和后代结局。
结果
资源母亲组达到代谢控制的平均周数为8.5（标准误=2.2），而对照组为16.1（标准误=1.7）。资源母亲组女性的婴儿出生时头围更大，发育商更高。
结论
本文所述的资源母亲计划改善了苯丙酮尿症孕妇的代谢控制。
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