Kawasumi T, Sato M, Tsuriya Y, Ueno S
Department of Food and Nutrition, Faculty of Home Economics, Japan Women's University, Tokyo, Japan.
Biosci Biotechnol Biochem. 1999 Mar;63(3):581-4. doi: 10.1271/bbb.63.581.
A koji-based medicine composed of powder of Aspergillus oryzae NK koji, dried yeast, and lactobacilli koji had high antioxidant activity measured by a modified t-butyl peroxyl radical scavenging assay. This activity was mainly derived from A. oryzae NK koji. Digestion of koji-making grain germ medium with several commercial enzymes also increased antioxidant activity. By two weeks of oral administration of A. oryzae NK koji, the serum lipid peroxide levels elevated in STZ-induced diabetic rats could be decreased significantly.
一种由米曲霉NK曲、干酵母和乳酸菌曲粉末组成的基于曲的药物，通过改良的叔丁基过氧自由基清除试验测定，具有较高的抗氧化活性。这种活性主要来源于米曲霉NK曲。用几种商业酶消化制曲谷物胚芽培养基也能提高抗氧化活性。通过对链脲佐菌素诱导的糖尿病大鼠口服米曲霉NK曲两周，可显著降低其血清脂质过氧化物水平。
