Links P S, Heslegrave R, van Reekum R
St. Michael's Hospital, Department of Psychiatry, Faculty of Medicine, University of Toronto, Canada.
J Pers Disord. 1999 Spring;13(1):1-9. doi: 10.1521/pedi.1999.13.1.1.
This prospective follow-up study addresses whether impulsivity versus other aspects of borderline personality disorder (BPD) are (1) stable over a 7-year follow-up period; (2) able to predict the persistence versus remittance of BPD over 7 years of follow-up, and (3) more predictive of the level of borderline psychopathology on follow-up than other aspects of the disorder. When the cohort was assembled, 88 of 130 subjects scored seven or higher on the Diagnostic Interview for Borderlines (DIB), indicating a definite diagnosis of BPD. The cohort was reassessed at 2 and 7 years after the index admission. At the 7-year follow up, 81(62.3%) of the original cohort were re-examined, two (1.6%) were deceased, six (4.6%) suicided, 36 (27.7%) refused to participate and five (3.8%) could not be located. The results indicated that the initial impulse action subscale score was highly correlated with the 7-year follow-up score (r = 0.53). Using a stepwise multiple regression technique, the impulse action subscale score from the DIB best predicted borderline psychopathology at the 7-year follow up, with an r2 of 0.24, F = 24.84, p < 0.001. This prospective study of subjects with BPD indicates that impulsivity is stable over time and highly predictive of borderline psychopathology over 7 years follow up. These results suggest the treatment of impulsivity may impact the course of BPD.
这项前瞻性随访研究探讨了冲动性与边缘型人格障碍(BPD)的其他方面是否(1)在7年的随访期内保持稳定;(2)能够预测BPD在7年随访期内的持续或缓解情况,以及(3)与该障碍的其他方面相比,对随访时边缘型精神病理学水平的预测性更强。在组建队列时,130名受试者中有88名在边缘型人格障碍诊断访谈(DIB)中得分达到7分或更高,表明确诊为BPD。该队列在首次入院后2年和7年时进行了重新评估。在7年随访时,对原队列中的81名(62.3%)进行了复查,2名(1.6%)已去世,6名(4.6%)自杀,36名(27.7%)拒绝参与,5名(3.8%)无法找到。结果表明,初始冲动行为分量表得分与7年随访得分高度相关(r = 0.53)。使用逐步多元回归技术,DIB中的冲动行为分量表得分在7年随访时对边缘型精神病理学的预测效果最佳,r2为0.24,F = 24.84,p < 0.001。这项对BPD患者的前瞻性研究表明,冲动性随时间推移保持稳定,并且在7年随访中对边缘型精神病理学具有高度预测性。这些结果表明,对冲动性的治疗可能会影响BPD的病程。