Gilboe I M, Husby G
Oslo City Department of Rheumatology, Diakonhjemmet Hospital, Norway.
Scand J Rheumatol. 1999;28(2):81-7. doi: 10.1080/030097499442531.
By reviewing patient's records, we evaluated the sensitivity and specificity of the 1982 revised classification criteria for systemic lupus erythematosus on a cohort of 346 Norwegian patients with connective tissue disease, seen at a rheumatology referral center in the period 1986-95. The patients with CTD other than SLE were used as controls. The number of the 1982 revised classification criteria for SLE fulfilled by each individual patient was calculated. Fifty-five of the 76 SLE patients (72%) met four or more criteria for SLE, giving a low sensitivity of 72%. Twenty-three of the 270 patients with CTD other than SLE (9%) met four or more criteria for SLE, giving an acceptable specificity of 91%. Applying the "revised/revised 1997 ACR criteria for SLE" the sensitivity would have increased to 78% and the specificity reduced to 89%. The sample of SLE patients was characterized by mild disease with a low proportion of severe internal manifestations.
通过查阅患者记录，我们对1982年修订的系统性红斑狼疮分类标准在1986年至1995年间于一家风湿病转诊中心就诊的346名挪威结缔组织病患者队列中的敏感性和特异性进行了评估。将除系统性红斑狼疮外的结缔组织病患者用作对照。计算了每位患者满足的1982年修订的系统性红斑狼疮分类标准的数量。76名系统性红斑狼疮患者中有55名（72%）符合四项或更多项系统性红斑狼疮标准，敏感性低至72%。270名除系统性红斑狼疮外的结缔组织病患者中有23名（9%）符合四项或更多项系统性红斑狼疮标准，特异性为可接受的91%。应用“1997年美国风湿病学会修订的系统性红斑狼疮标准”，敏感性将提高到78%，特异性将降至89%。系统性红斑狼疮患者样本的特点是病情较轻，严重内脏表现的比例较低。
