Giles D W, Miller S J, Rayan G M
Department of Orthopedic Surgery and Rehabilitation, University of Oklahoma Health Science Center/Baptist Medical Center, Oklahoma City 73112, USA.
Lasers Surg Med. 1999;24(3):187-93. doi: 10.1002/(sici)1096-9101(1999)24:3<187::aid-lsm3>3.0.co;2-v.
STUDY DESIGN/MATERIALS AND METHODS: Fourteen enchondromas, in eight patients, involving the tubular bones of the hand, were treated with curettage, CO2 laser sterilization of the tumor margins followed by autologous bone grafting. Average follow-up time was 35.4 months (14-106 months). Average patients age was 29 years.
At follow-up there were no clinical recurrences, none had pain, and all patients reported satisfactory hand function without limitations. Minimal decrease in range of motion without functional limitation was encountered following excision of two lesions (14%) in one patient. One patient reported an increase in range of motion after excision. Grip strength was only minimally decreased. There was no radiographic evidence of recurrence.
The use of CO2 laser is safe and effective as an adjunct to curettage and bone grafting in the management of relatively large enchondromas of the tubular bones of the hand.
研究设计/材料与方法：8例患者的14处内生软骨瘤累及手部管状骨，采用刮除术、CO2激光对肿瘤边缘进行消毒，随后进行自体骨移植治疗。平均随访时间为35.4个月（14 - 106个月）。患者平均年龄为29岁。
随访时无临床复发，均无疼痛，所有患者手部功能均满意且无受限。1例患者切除2处病变（14%）后，活动范围有轻微减小，但无功能受限。1例患者切除后活动范围增加。握力仅轻微下降。影像学检查无复发证据。
在手部管状骨相对较大的内生软骨瘤治疗中，CO2激光作为刮除术和骨移植的辅助手段是安全有效的。
