Yoshii S, Shimizu K, Ido K, Nakamura T
Department of Orthopaedic Surgery, Kansai-Denryoku Hospital, Osaka, Japan.
J Spinal Disord. 1999 Apr;12(2):157-61.
Ependymomas are the most common glial tumors of the spinal cord, including the conus medullaris, filum terminale, and cauda equina. This study involved eight ependymomas of the spinal cord encountered during a 29-year period (1968-1996). The male:female ratio was 1:1.7, and the mean age at diagnosis was 33.7 years (range, 13-55 years). The outcome was studied in relation to initial presentation, initial therapy, location of tumor, histology of tumor, and gender after a follow-up period ranging from 2-16 years (mean, 113 months). Complete removal was achieved in six patients. Two patients received postoperative irradiation after partial removal. Histological examination revealed a benign ependymoma in all patients. Patients undergoing gross total excision at initial operation had excellent or good outcomes. We conclude that ependymomas of the spinal cord should be removed completely, if possible. Spine surgeons should be aware of the disease, and magnetic resonance imaging should be used in its detection.
室管膜瘤是脊髓最常见的神经胶质瘤,包括圆锥、终丝和马尾。本研究纳入了29年间(1968 - 1996年)遇到的8例脊髓室管膜瘤。男女比例为1:1.7,诊断时的平均年龄为33.7岁(范围13 - 55岁)。在随访2 - 16年(平均113个月)后,研究了与初始表现、初始治疗、肿瘤位置、肿瘤组织学和性别的相关结果。6例患者实现了完全切除。2例患者在部分切除后接受了术后放疗。组织学检查显示所有患者均为良性室管膜瘤。初次手术时接受全切除的患者预后良好或极佳。我们得出结论,脊髓室管膜瘤应尽可能完全切除。脊柱外科医生应了解这种疾病,并且应使用磁共振成像进行检测。