Tikhonenko A S, Gachechiladze K K, Bespalova I A, Kretova A F, Chanishvili T G
Mol Biol (Mosk). 1976 Jul-Aug;10(4):667-73.
In an investigation of the antigenic fine structure of phages T4 and DDVI with the use of the neutralization reaction and electron-microscopic observation of the phage-antibody complexes, it has been possible to establish that the head of phage T4 consists of proteins which have antigenic determinants of two types: The first type is identical to the antigens of the head of phage DDVI, and the second type is apparently absent in phage DDVI. The phage DDVI head contains mostly determinants which are common to the phage T4 head, since it was not possible to detect antigenically specific components in the phage DDVI head. The tail sheaths of phage T4 and DDVI appear to be identical in the antigenic respect. A difference has been observed in the fibers and the base plates of the phages investigated. The presence of the following three types of antigens has been established: 1) common to phages T2, T4, and DDVI, 2) common to phages T4 and DDVI, and 3) specific for each phage investigated.
在一项利用中和反应及噬菌体 - 抗体复合物的电子显微镜观察来研究噬菌体T4和DDVI抗原精细结构的实验中，已能够确定噬菌体T4的头部由具有两种类型抗原决定簇的蛋白质组成：第一种类型与噬菌体DDVI头部的抗原相同，第二种类型在噬菌体DDVI中显然不存在。噬菌体DDVI头部大多含有与噬菌体T4头部共有的决定簇，因为在噬菌体DDVI头部无法检测到抗原特异性成分。噬菌体T4和DDVI的尾鞘在抗原方面似乎是相同的。在所研究的噬菌体的纤维和基板中观察到了差异。已确定存在以下三种类型的抗原：1）噬菌体T2、T4和DDVI共有的，2）噬菌体T4和DDVI共有的，3）所研究的每种噬菌体特有的。
