[Investigation of serological features and molecular heterogeneity of virion proteins of morphologically related phages].

Some interaction process peculiarites of morphologically related phate T4, DDVI and FI1 with the corresponding antiphageous sera in cross reactions of neutralisation have been investigated. Close serological relationship of phage T4 and DDVI was demonstrated. Inactivation of phage FI1 in these serological reactions showed anomalous nature and did not submit to the rules of the first step reaction. According to investigations of the protein component of virions of these phages by electrophoresis in polyacrylamide gel, phages T4 and DDVI contain twelve, FI1 and DDVI four, and T4 and FI1 two protein fractions common in molecular weight. The data obtained indicates that close serological relationship between phages T4 and DDVI is determined by the presence of common protein antigens in the absorptional apparatus of virions. Proteins of phage FI1, common with the proteins of T4 and DDVI, are obviously located in other structural components, and this determines the specific aggregation of virions in cross reactions of neutralization.