Suzuki K, Sonobe M, Matsutani M, Sugita K, Takahashi S
Department of Neurosurgery, Mito National Hospital, Ibaraki, Japan.
Childs Nerv Syst. 1999 Mar;15(2-3):134-6. doi: 10.1007/s003810050351.
We report on a germinoma in the suprasellar region, which had multiple large cystic components. A 13-year-old girl with disturbed visual acuity and growth retardation was admitted to our hospital for treatment of an intracranial tumor. The lesion was difficult to diagnose as a germinoma preoperatively, because of its radiographic characteristics. Histopathological examination revealed that the tumor was a germinoma. Surgery, chemotherapy with carboplatin and etoposide, and radiotherapy (30 Gy) were successful in inducing complete remission of the tumor. The patient's endocrine status remained normal, except for a low GH concentration and diabetes insipidus.
我们报告一例鞍上区域生殖细胞瘤，其具有多个大的囊性成分。一名13岁视力障碍和生长发育迟缓的女孩因颅内肿瘤入院接受治疗。由于其影像学特征，该病变术前难以诊断为生殖细胞瘤。组织病理学检查显示肿瘤为生殖细胞瘤。手术、卡铂和依托泊苷化疗以及放疗（30 Gy）成功诱导肿瘤完全缓解。除生长激素浓度低和尿崩症外，患者的内分泌状态保持正常。
