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马的实验性脊髓内马媾疫锥虫感染

Experimental intraspinal trypanosoma equiperdum infection in a horse.

作者信息

Barrowman P R

出版信息

Onderstepoort J Vet Res. 1976 Dec;43(4):201-2.

PMID:1023092
Abstract

To establish the ability of Trypanosoma equiperdum to cross the blood-brain-barrier in the horse, a susceptible stallion was infected via the cerebrospinal fluid of the subarachnoid space by lumbosacral puncture. Cerebrospinal fluid with low detectable levels of trypanosomes removed from a dourine-infected mare by lumbosacral puncture was used for infecting the animal. The parasite was detected in blood smears of the recipient 13 days after infection and the subsequent parasitaemia and clinical course of the disease followed that of naturally infected horses.

摘要

为确定马媾疫锥虫穿越马血脑屏障的能力,通过腰骶部穿刺经蛛网膜下腔的脑脊液感染一匹易感种公马。用通过腰骶部穿刺从一匹感染马媾疫的母马采集的、锥虫检测水平较低的脑脊液来感染该动物。感染13天后在受体的血涂片上检测到寄生虫,随后的寄生虫血症和疾病临床过程与自然感染马匹的情况相同。

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Experimental intraspinal trypanosoma equiperdum infection in a horse.马的实验性脊髓内马媾疫锥虫感染
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引用本文的文献

1
Dourine: a neglected disease of equids.马媾疫:一种被忽视的马属动物疾病。
Trop Anim Health Prod. 2017 Jun;49(5):887-897. doi: 10.1007/s11250-017-1280-1. Epub 2017 Apr 24.
2
First Draft Genome Sequence of the Dourine Causative Agent: Strain OVI.马媾疫病原体的初稿基因组序列:OVI菌株。
J Genomics. 2017 Jan 12;5:1-3. doi: 10.7150/jgen.17904. eCollection 2017.
3
Variable Surface Glycoprotein RoTat 1.2 PCR as a specific diagnostic tool for the detection of Trypanosoma evansi infections.可变表面糖蛋白RoTat 1.2聚合酶链反应作为检测伊氏锥虫感染的特异性诊断工具。
Kinetoplastid Biol Dis. 2004 Sep 17;3(1):3. doi: 10.1186/1475-9292-3-3.