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鸽子两性中重组节的频率相等,这表明与真兽亚纲哺乳动物存在根本差异。

Equal frequencies of recombination nodules in both sexes of the pigeon suggest a basic difference with eutherian mammals.

作者信息

Pigozzi M I, Solari A J

机构信息

Centro de Investigaciones en Reproduccion, Facultad de Medicina, Buenos Aires, Argentina.

出版信息

Genome. 1999 Apr;42(2):315-21.

PMID:10231963
Abstract

The total number of recombination nodules (RNs) in the autosomal synaptonemal complexes (SCs) is statistically equivalent in oocytes and spermatocytes from the domestic pigeon Columba livia. The distribution on RNs along the three longest autosomes is also equivalent in oocytes and spermatocytes. The numbers of RNs show a linear relationship when plotted against SC length both in oocytes and spermatocytes. On the other hand, the ZW pair shows a single and strictly localized RN near the synaptic termini, but the ZZ pair shows unrestricted location of RNs (average 3.8). The ZW and ZZ pairs of the pigeon are euchromatic and do not show specific chromatin packing at pachytene in either sex. The lack of sex-specific differences in the number and location of RNs in the autosomal bivalents of C. livia and previous data on the chicken, suggest that the regulation of crossing-over is basically different in birds and mammals.

摘要

家鸽(Columba livia)卵母细胞和精母细胞常染色体联会复合体(SCs)中重组结节(RNs)的总数在统计学上是相等的。卵母细胞和精母细胞中RNs沿三条最长常染色体的分布也是相等的。在卵母细胞和精母细胞中,将RNs的数量与SC长度作图时,二者呈线性关系。另一方面,ZW染色体对在突触末端附近显示单个且严格定位的RN,但ZZ染色体对显示RNs位置不受限制(平均3.8个)。家鸽的ZW和ZZ染色体对是常染色质,在任何性别的粗线期都不显示特定的染色质包装。家鸽常染色体二价体中RNs数量和位置缺乏性别特异性差异,以及之前关于鸡的数据表明,鸟类和哺乳动物中交叉互换的调控基本不同。

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