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患有未矫正先天性冠状动脉至肺动脉瘘的母亲行剖宫产术。

Cesarean section in a mother with uncorrected congenital coronary to pulmonary artery fistula.

作者信息

Tay S M, Ong B C, Tan S A

机构信息

Department of Anesthesia & Surgical Intensive Care, Singapore General Hospital, Singapore.

出版信息

Can J Anaesth. 1999 Apr;46(4):368-71. doi: 10.1007/BF03013230.

Abstract

PURPOSE

We report a case of a 33 yr old woman with pulmonary hypertension secondary to uncorrected right coronary artery to pulmonary artery fistula who underwent two successful operative deliveries under general anesthesia.

CLINICAL FEATURES

This woman underwent an emergency Caesarean section at 32 wk gestation because she presented in NYHA Class IV, heart failure and premature labour. She did not have antenatal follow-up. For her second pregnancy, she was managed from the first trimester of pregnancy by the cardiologist, obstetrician and anesthesiologist. She received oral furosemide and digoxin from eight weeks gestation. Pregnancy was managed to term before she progressed to NYHA Class IV and cardiac failure at 37 wk gestation. She had a Caesarean section under general anesthesia. She received rapid sequence induction of anesthesia and tracheal intubation with 0.1 mg x kg(-1) etomidate, 2 mg x kg(-1) succinylcholine and maintenance with nitrous oxide 50% in oxygen, isoflurane 1% and 0.1 mg x kg(-1) vecuronium. Fentanyl, 2 microg x kg(-1) helped to obtund the hypertensive response to intubation. Analgesia was provided with 1 mg x kg(-1) morphine. Glyceryl trinitrate infusion, 10-30 microg x min(-1) was used in addition to the anti-heart failure therapy. End-tidal capnography, electrocardiogram, pulse oximetry, continuous arterial blood pressure and pulmonary arterial catheter provided hemodynamic monitoring. The lungs were mechanically ventilated for 24 hr postoperatively. She received anti-heart failure therapy which she continued after discharge. She was NYHA class II upon discharge. She defaulted from further follow-up.

CONCLUSION

Although the literature advocates, in this situation, controlled vaginal delivery utilising epidural analgesia, we describe the successful outcome for operative delivery under general anesthesia in a patient with secondary pulmonary hypertension and heart failure.

摘要

目的

我们报告一例33岁女性患者,其患有继发于未矫正的右冠状动脉至肺动脉瘘的肺动脉高压,在全身麻醉下成功进行了两次剖宫产分娩。

临床特征

该女性在妊娠32周时因出现纽约心脏协会(NYHA)IV级心力衰竭和早产而接受了急诊剖宫产。她没有产前随访。在第二次怀孕时,从妊娠早期开始由心脏病专家、产科医生和麻醉医生共同管理。她从妊娠8周开始接受口服速尿和地高辛治疗。妊娠持续至足月,在妊娠37周时病情进展至NYHA IV级和心力衰竭之前进行了剖宫产。她在全身麻醉下接受了剖宫产。她接受了快速顺序诱导麻醉和气管插管,使用了0.1mg/kg依托咪酯、2mg/kg琥珀酰胆碱,并以50%氧化亚氮、1%异氟烷和0.1mg/kg维库溴铵维持麻醉。2μg/kg芬太尼有助于减轻插管时的高血压反应。使用1mg/kg吗啡提供镇痛。除抗心力衰竭治疗外,还使用了10 - 30μg/min的硝酸甘油输注。呼气末二氧化碳监测、心电图、脉搏血氧饱和度、连续动脉血压和肺动脉导管进行血流动力学监测。术后肺部机械通气24小时。她接受了抗心力衰竭治疗,出院后继续使用。出院时她为NYHA II级。她未进行进一步随访。

结论

尽管文献主张在这种情况下使用硬膜外镇痛进行可控阴道分娩,但我们描述了一例继发肺动脉高压和心力衰竭患者在全身麻醉下剖宫产分娩的成功结果。

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