Sirigu P, Diaz G, Lantini M S, Del Fiacco M
Riv Istochim Norm Patol. 1976;20(4):159-66.
The localization of lipids in the secretion of human parotid and submandibular glands has been here investigated. Ultrastructural observations following lipid extraction and histochemical data showed that lipid components are not present in the secretory granules. In fact, while histochemical reactions are completely negative, secretory granules from lipid-depleted glands retain all their morphological characters. These results led us to emphasize that, at least in human seromucous cells, lipids are not directly involved in the salivary secretion. This conclusion, which is supported by the biochemical data concerning the lipid content in human saliva, disagrees with the findings obtained in rat and guinea pig salivary glands. However, this discrepancy may be ascribed to the specific biochemical and ultrastructural differences found in the salivary glands of the various mammalian species.
本文对人腮腺和颌下腺分泌物中脂质的定位进行了研究。脂质提取后的超微结构观察及组织化学数据表明，分泌颗粒中不存在脂质成分。事实上，组织化学反应完全呈阴性，而来自脂质耗尽腺体的分泌颗粒保留了其所有形态特征。这些结果使我们强调，至少在人浆液性黏液细胞中，脂质并不直接参与唾液分泌。这一结论得到了有关人唾液脂质含量的生化数据的支持，但与在大鼠和豚鼠唾液腺中获得的结果不同。然而，这种差异可能归因于在各种哺乳动物唾液腺中发现的特定生化和超微结构差异。
