Zaets T L, Koriakina I K, Komkina T I, Podoprigora G I
Biull Eksp Biol Med. 1976 Dec;82(12):1444-6.
Experiments were conducted on germ-free (gnotobiotic) rats. A study was made of the toxic properties of the organs and the activity of proteolytic enzymes in them after thermal burns. Despite the absence of pathogenic microbial flora the germ-free rats developed the state of toxemia with an increase of the level of proteolytic enzymes. The extent of the toxic and catabolic reaction depended on the severity of the burn. Intoxication and an increase in proteolysis in the gnotobiotic rats were similar, and, in a number of cases greater than in usual animals. A conclusion was drawn on the important role of the tissue sources of intoxication in burns. A correlation between the toxemia and proteolysis was established.
在无菌（悉生）大鼠身上进行了实验。研究了热烧伤后大鼠器官的毒性特性及其内蛋白水解酶的活性。尽管无菌大鼠体内不存在致病微生物菌群，但它们仍出现了毒血症状态，且蛋白水解酶水平升高。毒性和分解代谢反应的程度取决于烧伤的严重程度。无菌大鼠的中毒和蛋白水解增加情况相似，且在许多情况下比普通动物更严重。得出了关于烧伤中毒组织来源的重要作用的结论。确定了毒血症与蛋白水解之间的相关性。
