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[烧伤免疫治疗的实验研究]

[Experimental study of the immunotherapy of burns].

作者信息

Fedorov N A, Koriakina I K, Zaets T L, Khlystova Z S, Tokareva O I

出版信息

Biull Eksp Biol Med. 1977 Nov;84(11):534-7.

PMID:588725
Abstract

Experiments were conducted on rats. The influence of the serum of a burn convalescent on the toxic properties, the level of proteolytic enzymes activity, and morphological changes following burn were studied. After the burn the blood serum and the extracts of the organs acquired toxic properties; there was an increase in the activity of proteolytic enzymes, and marked morphological changes developed Administration of the serum of aburn convalescent promoted detoxication, diminished the activity of proteolytic enzymes distinctly, and decreased the morphological disturbances.

摘要

在大鼠身上进行了实验。研究了烧伤康复者血清对烧伤后毒性特性、蛋白水解酶活性水平及形态变化的影响。烧伤后,血清和器官提取物具有毒性特性;蛋白水解酶活性增加,并出现明显的形态变化。给予烧伤康复者血清可促进解毒,显著降低蛋白水解酶活性,并减轻形态学紊乱。

相似文献

1
[Experimental study of the immunotherapy of burns].[烧伤免疫治疗的实验研究]
Biull Eksp Biol Med. 1977 Nov;84(11):534-7.
2
[Toxicity and proteolysis in gnotobiotic rats with thermal burns].[无菌大鼠热烧伤后的毒性与蛋白水解作用]
Biull Eksp Biol Med. 1976 Dec;82(12):1444-6.
3
[On the characteristics of proteolytic enzymes in rabbit tissue after thermal burn].[关于热烧伤后兔组织中蛋白水解酶的特性]
Vopr Med Khim. 1969 Jan-Feb;15(1):43-7.
4
[The effect of trypsin on the toxicity and proteolytic activity of the serum and organs in thermal burns].[胰蛋白酶对热烧伤时血清及器官毒性和蛋白水解活性的影响]
Biull Eksp Biol Med. 1974 Nov;78(11):47-9.
5
[Enzyme activity in animal organs during burn shock].
Biull Eksp Biol Med. 1973 Oct;75(10):56-8.
6
[Changes of proteolytic enzyme activity and toxic properties of serum and organ extracts of rats with burns against the background of contrykal administration].[在使用抑肽酶的情况下,烧伤大鼠血清和器官提取物的蛋白水解酶活性及毒性特性的变化]
Patol Fiziol Eksp Ter. 1979 Mar-Apr(2):41-5.
7
[Changes in skin enzyme activity in experimental burns].
Vopr Med Khim. 1977 Nov-Dec(6):763-8.
8
Insulin-induced changes of proteolytic activity of the lysosomal enzymes.胰岛素引起的溶酶体酶蛋白水解活性的变化。
Neuro Endocrinol Lett. 2004 Feb-Apr;25(1-2):83-6.
9
Nature of the toxicity of the serum and organs of rats after thermal burns.热烧伤后大鼠血清及器官的毒性性质。
Bull Exp Biol Med. 1974 Jun;76(12):1396-7. doi: 10.1007/BF00787541.
10
[Nature of the toxicity of rat serum and organs following thermal burns].[热烧伤后大鼠血清及器官的毒性性质]
Biull Eksp Biol Med. 1973 Dec;76(12):17-9.