[胸腺切除小鼠中卡介苗的致死性感染]
[Lethal infection with BCG in thymectomized mice].
作者信息
Moroz A M, Galkin Iu M, Litvinov V I, Il'ina I N, Averbakh M M
出版信息
Biull Eksp Biol Med. 1976 Dec;82(12):1464-5.
PMID:1023978
Abstract
Investigations carried out on CBA mice demonstrated that adult mice to which mycobacteria BCG were injected intravenously 12 months after thymectomy (in a dose of 2 mg for a period of 2 1/2 months) died of disseminated BCG infection against the background of depression of hypersensitivity of delayed type. The usual vaccine process developed in the sham-operated animals.
摘要
对CBA小鼠进行的研究表明，在胸腺切除术后12个月静脉注射卡介苗（剂量为2毫克，持续2个半月）的成年小鼠，在迟发型超敏反应受到抑制的情况下死于播散性卡介苗感染。而假手术动物则出现了通常的疫苗反应过程。
Zotero 插件