[维生素E缺乏症期间脂质过氧化及通过肌浆网膜的钙离子转运紊乱]
[Lipid peroxidation and disturbance in Ca2+ transport through sarcoplasmic reticulum membranes during E-avitaminosis].
作者信息
Arkhipenko I U, Gazdarov A K, Kagan V E, Kozlov Iu P, Spirichev V B
出版信息
Biokhimiia. 1976 Oct;41(10):1898-902.
PMID:1024582
Abstract
The antioxidant effect of alpha-tocopherol in biolgoical membranes in vivo is described. Experimental E-avitaminosis is accompanied by accumulation of products of free-radical oxidation of phospholipids and by a loss of Ca2+-transporting ability of the muscle cells microsomal fraction. The role of alpha-tocopherol in stabilization and as a "radical trap" in biological membranes is discussed.
摘要
描述了α-生育酚在体内生物膜中的抗氧化作用。实验性维生素E缺乏症伴随着磷脂自由基氧化产物的积累以及肌肉细胞微粒体部分钙转运能力的丧失。讨论了α-生育酚在生物膜稳定化中的作用以及作为“自由基陷阱”的作用。
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