Creutzig H
Eur J Nucl Med. 1976 Aug 12;1(3):177-80. doi: 10.1007/BF00257968.
Bone imaging was done in patients after total replacement arthroplasty of the hip joint every 3rd month using 99mTc-HEDP and 18F. Uptake ratios were estimated over cup/normal hip and femur prosthesis/normal thigh. Ratios decline rapidly and reach a stable level 6-9 months, postoperatively. Eight cases of late infection were predicted correctly 1-3 months before any radiologic evidence was present. In four cases there had been false-positive results with 99mTc-HEDP while 18F gave always correct information except in cases of soft tissue inflammation. Here both 99mTc-HEDP and 18F ratios were elevated. The early diagnosis of late complications after replacement arthroplasty seems to be possible. The clinical significance, however, is low: only one out of eight patients with manifest infection is still on conservative treatment. Bone imaging should be done to exclude late infection as a cause of pain after total replacement arthroplasty of the hip joint only.
在髋关节全置换术后的患者中，每隔3个月使用99m锝-羟基亚乙基二膦酸盐（99mTc-HEDP）和18F进行骨显像。计算髋臼/正常髋关节以及股骨假体/正常大腿的摄取率。摄取率术后迅速下降，6至9个月后达到稳定水平。8例迟发性感染在出现任何放射学证据前1至3个月就被正确预测。4例使用99mTc-HEDP时有假阳性结果，而18F除了软组织炎症病例外，总能提供正确信息。在软组织炎症病例中，99mTc-HEDP和18F的摄取率均升高。髋关节置换术后迟发性并发症的早期诊断似乎是可行的。然而，其临床意义不大：8例有明显感染的患者中只有1例仍在接受保守治疗。仅在髋关节全置换术后，应进行骨显像以排除迟发性感染作为疼痛原因。
